Save 60% Off all remaining inventory with Promo Code: ICE

Study: CBD Could Help Boost Effects Of Some Common Anti-Epilepsy Meds

January 01, 2018

Not only has cannabis been proven to be effective in treating epilepsy, but recent studies show it can also help boost the effects of standard epilepsy medications

Aside from epilepsy medication, cannabis can also increase the effectiveness of a variety of other medications such as blood pressure treatments, pain relief pills, and medications used by cancer patients. Because cannabis can interfere with the liver’s cytochrome p450 enzyme system, which is the body’s method of processing chemicals, certain drugs can show increased levels in the blood and heightened effects when paired with cannabis.

The Research

In a recent study published in the Official Journal of the International League Against Epilepsy, 81 people were given doses of CBD and studied, with positive results. “In 39 adults and 42 children, CBD dose was started at 5 mg/kg/day and increased every 2 weeks by 5 mg/kg/day up to a maximum of 50 mg/kg/day,” the article noted. “Serum AED levels were obtained at baseline prior to CBD initiation and at most study visits.”

This procedure was used to determine if there was any change in the AED serum levels following increasing doses of CBD. The study went on to mention “subanalyses were performed to determine if the frequency of sedation in participants was related to the mean serum N-desmethylclobazam level, and if aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels were different in participants taking concomitant valproate.”

The Results

The research shows that the interactions between cannabidiol and common anti-epilepsy drugs can be quite significant. “Increases in topiramate, rufinamide, and N-desmethylclobazam and decrease in clobazam (all p < 0.01) serum levels were seen with increasing CBD dose. Increases in serum levels of zonisamide (p = 0.02) and eslicarbazepine (p = 0.04) with increasing CBD dose were seen in adults. Except for clobazam and desmethylclobazam, all noted mean level changes were within the accepted therapeutic range. Sedation was more frequent with higher N-desmethylclobazam levels in adults (p = 0.02), and AST/ALT levels were significantly higher in participants taking concomitant valproate (p < 0.01).”

More research needs to be done to determine how many other conditions this could be beneficial for, but it could eventually lead to many patients using minimal amounts of prescription drugs and simply boosting the effects with an all-natural cannabis supplement. A truly safer way to medicate.

[Image credit: Pixabay]

The post Study: CBD Could Help Boost Effects Of Some Common Anti-Epilepsy Meds appeared first on Cannadelics.





Also in Education

Owning Guns is a Constitutional Right, Unless You’re a Cannabis User

September 28, 2022

Take two of the most hot-button, tendentious issues of our time – cannabis use and gun rights – combine them, and now we really have a debate. As the law currently stands, medical cannabis patients are not afforded their 2nd amendment right to bear arms. Technically, all cannabis consumers are banned from buying guns, but only medical […]

The post Owning Guns is a Constitutional Right, Unless You’re a Cannabis User appeared first on Cannadelics.

Continue Reading

Cannabis policy changes in Africa are welcome. But small producers are the losers

September 28, 2022

TESTSTSARDSAR

Cannabis policy changes in Africa are welcome. But small producers are the losers by Clemence Rusenga

Cannabis is a drug crop with a long history in Africa. Alongside coca and opium poppy, it has been subjected to international control for nearly a century. The International Opium Convention of 1925 institutionalised the international control system and extended the scope of control to cannabis. In 1961 a new international convention was adopted to […]

A link to your site, with your site's name and description as anchor text.

Continue Reading

University of Sydney to Offer Free Cannabis Testing

September 27, 2022

TESTSTSARDSAR

University of Sydney to Offer Free Cannabis Testing by Johnny Green

The University of Sydney is launching a fairly robust study in an attempt to, as the university describes it, “investigate cannabis consumption, behaviours, and attitudes among users.” Part of the study involves offering free, anonymous cannabis testing for people that cultivate their own cannabis in the Australian Capital Territory (ACT). Cannabis was decriminalized in 2020 in the […]

A link to your site, with your site's name and description as anchor text.

Continue Reading

Inventory Clearance Sale

Save 60% Off all remaining inventory with Promo Code: ICE